In the early 1980s there was a national push to interest women in engineering. The female engineering students at Marquette University, including Little Sisters of both Sigma Phi Delta and Triangle Fraternities, started meeting in hopes of forming an organization to increase the number of women in engineering. They decided to form a Sorority, and Alpha Omega Epsilon was founded on November 13, 1983. On March 22, 1984, the Associated Students of Marquette University voted on and approved the constitution, and Alpha Omega Epsilon became a recognized student organization on Marquette University's campus. As a recognized local sorority, Alpha Omega Epsilon was represented at the 1984-85 Panhellenic Conference winning the Presidential office and attaining representatives. The first Alpha Chapter candidate class was initiated in the Fall of 1984 which nearly doubled its membership from the twenty-seven founding members.

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Alpha Omega Epsilon celebrated 35 years of success on November 13, 2018. We now have over 45 active chapters in 4 regions across the United States and Canada. The Organization's mission has since expanded to include folks who are not only in both engineering and technical science, but also those who support these fields and align themselves with our values.